When attempting to starting the LispWorks X11/Motif GUI when the required version of Motif is not installed, LispWorks prints the error message:
Error: Could not register handle for external module X-UTILITIES::CAPIX11:
dyld: /Applications/LispWorks 6.1/lispworks-6-1-0-macos-universal-motif can't open library: /usr/local/lib/libXm.4.dylib (No such file or directory, errno = 2)
Ensure you install Motif as described in The X11 GTK+ and Motif GUIs. Restart X11.app and LispWorks after installation of Motif.
LispWorks Release Notes and Installation Guide - 23 Dec 2011