*autoload-asdf-integration* is consulted used when the LispWorks IDE starts. If its value is true, then the system arranges for ASDF integration code to be loaded automatically when ASDF is loaded.
The ASDF integration code makes the LispWorks IDE tools (System Browser, Search Files) work with ASDF systems (defined with
asdf:defsystem) as well as 'native' systems defined with defsystem.
See Using ASDF for more information about using ASDF with LispWorks.
LispWorks User Guide and Reference Manual - 20 Sep 2017