Run LispWorks (all variants) from the directory
The LispWorks executable is named as shown here:.
This executable should not be moved without being resaved because it needs to be able to locate the corresponding library directory on startup.
When you run LispWorks, the splashscreen should appear, followed by the LispWorks Podium and a Listener. See Troubleshooting for details if this does not happen.
LispWorks Release Notes and Installation Guide - 23 Dec 2011